Effects of Acute Hepatic and Renal Failure on Pharmacokinetics of Flunixin Meglumine in Rats
نویسندگان
چکیده
منابع مشابه
Effects of acute hepatic and renal failure on pharmacokinetics of flunixin meglumine in rats.
The aim of this study was to investigate the effects of hepatic and renal failure on the pharmacokinetics of flunixin in carbon tetrachloride (CCl(4))- and glycerol-treated rats. After intravenous administration of flunixin (2 mg/kg), the plasma concentration of flunixin was measured by high-performance liquid chromatography. Both acute hepatic and renal failure resulted in significantly increa...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 2011
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.60.187